The British Journal of Psychiatry 150: 863-864 (1987)
© 1987 The Royal College of Psychiatrists
Clonidine. An effective anti-manic agent?
J Maguire and AN Singh
St Brigid's Hospital, Ardee, Eire.
Three patients suffering from bipolar affective disorder, manic phase, and
who were resistant to conservative treatment were successfully treated with
clonidine. This would support the nor-adrenergic hyperactivity theory of
mania. The rapidity of action of clonidine and its lack of relatively
serious side-effects renders it a potential alternative to conventional
anti-manic agents.