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The British Journal of Psychiatry 150: 653-655 (1987)
© 1987 The Royal College of Psychiatrists

A comparative trial of a new antidepressant, fluoxetine

S Levine, R Deo and K Mahadevan
Oldham and District General Hospital.

This clinical trial of a new antidepressant, fluoxetine, shows it to be as effective as a standard tricyclic drug, imipramine. It is effective as a single daily dose and is free of any significant side-effects. It is less sedative and appears to cause fewer problems of weight increase. The three scales used to assess efficacy showed a very positive correlation.


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Copyright © 1987 The Royal College of Psychiatrists.