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The British Journal of Psychiatry 150: 547-549 (1987)
© 1987 The Royal College of Psychiatrists

Cousin marriages and schizophrenia in Saudi Arabia

K Chaleby and TA Tuma
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

The rate and degree of consanguinity in the parents of 143 schizophrenics who satisfied the DSM-III diagnostic criteria, was compared in the same number of controls matched for age, sex and socioeconomic class. A family history of disorders suggestive of schizophrenia in the offspring of consanguineous parents who were schizophrenic, was compared with the incidence of a similar history in the schizophrenic offspring of non-consanguineous parents. There was no statistically significant difference in the former, but there was in the latter. This finding supports the theory of a familial tendency towards schizophrenia and the possibility of recessive or a multigene pattern of inheritance.


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Copyright © 1987 The Royal College of Psychiatrists.