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The British Journal of Psychiatry 149: 787-789 (1986)
© 1986 The Royal College of Psychiatrists
HY Knobler, S Itzchaky, D Emanuel, R Mester and S Maizel
Two bipolar depressed patients and one unipolar depressed patient developed manic symptoms after receiving trazodone. The symptoms resolved when the treatment was discontinued or reduced. We believe the two bipolar patients are the first cases of this reaction reported in the literature.
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