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The British Journal of Psychiatry 149: 627-630 (1986)
© 1986 The Royal College of Psychiatrists

An American validation study of the Newcastle diagnostic scale. I. Relationship with the dexamethasone suppression test

M Zimmerman, B Pfohl, D Stangl and W Coryell

The Newcastle diagnostic index was completed on 159 depressed in- patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after controlling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.




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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1986 The Royal College of Psychiatrists.