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The British Journal of Psychiatry 148: 648-654 (1986)
© 1986 The Royal College of Psychiatrists

Psycho-social predictors of chronicity in depressed patients

RM Hirschfeld, GL Klerman, NC Andreasen, PJ Clayton and MB Keller

Nineteen patients with an episode of major depressive disorder who did not recover within two years of prospective follow-up were compared with an equal number who recovered within a year of the initial evaluation and remained well through the two-year follow-up date. The groups were individually matched for age, sex, primary/secondary status, and prior duration of episode. The only psycho-social variable that predicted chronicity was increased neuroticism on self-report personality inventories administered during the index evaluation. Early loss, recent life events, and recent social supports were not predictive of outcome.


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Copyright © 1986 The Royal College of Psychiatrists.