The British Journal of Psychiatry 147: 419-423 (1985)
© 1985 The Royal College of Psychiatrists
The dexamethasone suppression test and suicidal patients
J Ennis, RA Barnes and S Kennedy
The dexamethasone suppression test (DST) was used in an in-patient crisis
unit to determine whether the test could identify suicidal patients who
might benefit from tricyclic antidepressants. DST results, DSM-III
diagnoses, and measures of symptom levels were obtained for 72 patients
admitted for a 3-5 day period; 31 were non-suppressors. Abnormal DST
results were not related to DSM-III diagnosis or to scores on measures of
depression and symptom levels. Only three patients met DSM-III criteria for
major depression with melancholia; 26 patients had a diagnosis of alcohol
or substance abuse. The poor specificity of the DST in this patient
population suggests that its routine use in such patients could be highly
misleading.