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The British Journal of Psychiatry 146: 490-497 (1985)
© 1985 The Royal College of Psychiatrists

Mates of schizophrenic mothers. A study of assortative mating from the American-Danish high risk project

J Parnas

Both mates of schizophrenic mothers and a control group consisting of mates of non-schizophrenic mothers were diagnostically examined. The former were more frequently psychiatrically deviant than their controls, both with respect to a life-time syndrome diagnosis and a personality diagnosis. Mating between a schizophrenic mother and a father who suffered from schizophrenia spectrum disorder significantly increased the offspring's risk of developing a schizophrenia spectrum disorder himself. Assortative mating was negatively correlated with age of onset of maternal schizophrenia. It is proposed that defective emotional rapport or sub-psychotic features constitute the phenotypic traits by which assortative mating operates in schizophrenia.


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L. T. Niemi, J. M. Suvisaari, J. K. Haukka, G. Wrede, and J. K. Lonnqvist
Cumulative incidence of mental disorders among offspring of mothers with psychotic disorder: Results from the Helsinki High-Risk Study
The British Journal of Psychiatry, July 1, 2004; 185(1): 11 - 17.
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Copyright © 1985 The Royal College of Psychiatrists.