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The British Journal of Psychiatry 144: 64-69 (1984)
© 1984 The Royal College of Psychiatrists

Impact of lithium therapy on core psychotic symptoms of schizophrenia

FP Zemlan, J Hirschowitz, FJ Sautter and DL Garver

The authors have previously reported that a sub-group of schizophrenic- like patients respond favorably to lithium therapy: furthermore, psychotic patients who respond to lithium demonstrate appreciable improvement during the first seven days of treatment. The present study investigated which symptoms of schizophrenia improved quickly during lithium treatment. We found that patients who do respond to lithium show significant improvement in the core symptoms of psychosis-- hallucinations, delusions and formal thought disorder--during the first seven days of treatment, thus allowing early identification of 88 per cent of schizophrenic patients who ultimately respond to lithium and 91 per cent of those who do not.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1984 The Royal College of Psychiatrists.