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The British Journal of Psychiatry 132: 555-559 (1978)
© 1978 The Royal College of Psychiatrists

A controlled trial of L-tryptophan in mania

CA Chambers and GJ Naylor

A double-blind placebo-controlled trial of L-tryptophan, with pyridoxine and ascorbic acid, was carried out in 10 female patients suffering from mania. In contrast to earlier studies led by Prange and Murphy, L-tryptophan was found to be no better than placebo.




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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1978 The Royal College of Psychiatrists.