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The British Journal of Psychiatry 132: 149-151 (1978)
© 1978 The Royal College of Psychiatrists

Histocompatability antigens and schizophrenia

P McGuffin, AE Farmer and SM Rajah

The HLA (Human Leucocyte Antigen) types and B were studied in 80 patients diagnosed as schizophrenic. There was an increased incidence of HLA-BW5 and a decrease in HLA-AW29 and HLA-BW17 as compared with healthy controls. In the sub-group of patients exhibiting Schneider's first-rank symptoms there was an increased incidence of HLA-A1 with a decrease in HLA-A2 and HLA-BW17.




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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1978 The Royal College of Psychiatrists.