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The British Journal of Psychiatry 128: 451-455 (1976)
© 1976 The Royal College of Psychiatrists

A controlled trial of phenothiazine withdrawal in chronic schizophrenic patients

P Andrews, JN Hall and RP Snaith

Phenothiazine drugs were withdrawn from 17 chronic schizophrenic in- patients, with a control group of 14 patients remaining on active medication. The trial was conducted under double blind conditions over a period of 42 weeks with weekly assessment of the patients by ward nurses. Of the placebo group 35% relapsed, relapse being related to the level of previous active medication.


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Copyright © 1976 The Royal College of Psychiatrists.