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1 Senior Registrars, The Maudsley Hospital, London, SE5 8AZ
A replication study of the effects of single-night sleep deprivation therapy was carried out as a preliminary to a controlled comparison with orthodox antidepressant measures. The results show that sleep deprivation therapy was acceptable to a majority of the patients studied, and was followed by an improvement in over half those who completed treatment. Adverse effects were minimal. The authors feel that further clinical and physiological study is warranted.
Submitted on October 10, 1974
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T. A. Wehr, F. K. Goodwin, A. Wirz-Justice, J. Breitmaier, and C. Craig 48-Hour Sleep-Wake Cycles in Manic-Depressive Illness: Naturalistic Observations and Sleep Deprivation Experiments Arch Gen Psychiatry, May 1, 1982; 39(5): 559 - 565. [Abstract] [PDF] |
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