BJP RCPsych Publications
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
QUICK SEARCH:   [advanced]


     

The British Journal of Psychiatry (1974) 125: 496-499. doi: 10.1192/bjp.125.5.496
© 1974 The Royal College of Psychiatrists
This Article
Right arrow Full Text (PDF)
Right arrow Submit an eLetter
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by KILOH, L. G.
Right arrow Articles by ANDREWS, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by KILOH, L. G.
Right arrow Articles by ANDREWS, G.

Response of Depressed Patients to Methylamphetamine

L. G. KILOH M.D., F.R.C.P., F.R.C.Psych., F.A.N.Z.C.P.1, MEGAN NEILSON B.Sc.2, and GAVIN ANDREWS M.D., M.R.C.Psych., M.A.N.Z.C.P.3

1 Professor of Psychiatry, School of Psychiatry, University of New South Wales, The Prince Henry Hospital, Little Bay, N.S.W. 2036, Australia
2 Scientific Officer, School of Psychiatry, University of New South Wales, The Prince Henry Hospital, Little Bay, N.S.W. 2036, Australia
3 Associate Professor, School of Psychiatry, University of New South Wales, The Prince Henry Hospital, Little Bay, N.S.W. 2036, Australia

One hundred and ninety-one patients, including 39 with endogenous depression and 56 with neurotic depression were each given 15 mg. methylamphetamine intravenously. There was a strong tendency for all patients—including those with schizophrenia—to feel better, irrespective of diagnosis. No significant difference was found between the responses of patients with neurotic and those with endogenous depression. No significant relationship was established between prognosis on discharge from hospital and six months later in any diagnostic group.

Those patients who felt worse after methylamphetamine showed a high incidence of hysterical symptoms and/or hysterical personality traits (p < 0.0005). Among those reporting no change there was a significant preponderance of those dependant on drugs or alcohol.

The response to intravenous methylamphetamine would appear to have no diagnostic or prognostic significance in patients with depressive illnesses.

Submitted on February 18, 1974




This article has been cited by other articles:


Home page
 Arch Gen PsychiatryHome page
D. P. van Kammen, J. P. Docherty, S. R. Marder, S. C. Schulz, L. Dalton, and W. E. Bunney Jr
Antipsychotic Effects of Pimozide in Schizophrenia: Treatment Response Prediction With Acute Dextroamphetamine Response
Arch Gen Psychiatry, March 1, 1982; 39(3): 261 - 266.
[Abstract] [PDF]

Home page
 Arch Gen PsychiatryHome page
D. P. van Kammen, J. P. Docherty, S. R. Marder, J. N. Rayner, and W. E. Bunney Jr
Long-term Pimozide Pretreatment Differentially Affects Behavioral Responses to Dextroamphetamine in Schizophrenia: Further Exploration of the Dopamine Hypothesis of Schizophrenia
Arch Gen Psychiatry, March 1, 1982; 39(3): 275 - 281.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1974 The Royal College of Psychiatrists.