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The British Journal of Psychiatry (1974) 125: 275-279. doi: 10.1192/bjp.125.3.275
© 1974 The Royal College of Psychiatrists
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Urinary Excretion of Adenosine 3 :5-Cyclic Monophosphate in Depressive Illness

G. J. NAYLOR M.D., B.Sc., M.R.C.Psych.1, D. A. STANSFIELD B.Sc., Ph.D.2, S. F. WHYTE M.B., Ch.B., B.Sc., D.P.M.3, and F. HUTCHINSON B.Sc., Ph.D.4

1 Senior Lecturer, Department of Psychiatry, University of Dundee, Dundee, Scotland
2 Senior Lecturer, Department of Biochemistry, University of Dundee
3 Lecturer, Department of Psychiatry, University of Dundee, Senior Registrar, Southern General Hospital, Glasgow, S.W.1
4 Deputy Regional Physicist, Regional Physics Department, 7 Dudhope Terrace, Dundee

The urinary excretion of cyclic AMP was estimated in 12 patients suffering from a depressive psychosis and estimated again when they had recovered. During each period of assessment the patients were maintained under metabolic ward conditions.

The urinary excretion of cyclic AMP increased significantly with recovery. The urine volume showed no significant change with recovery and did not correlate significantly with the cyclic AMP excretion.







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Psychiatric Bulletin Advances in Psychiatric Treatment All RCPsych Journals
Copyright © 1974 The Royal College of Psychiatrists.