Severe Shock Caused by Chlorpromazine Hypersensitivity
PANG L. MAN M.D.1 and
CALVIN H. CHEN M.D., M.Sc.2
1 Director of Research, Northville State Hospital, Northville, Michigan, 48167, U.S.A.
2 Assistant Medical Superintendent, Northville State Hospital, and Adjunct Assistant Professor of Psychiatry, Wayne State University, Detroit, Michigan
In this paper the authors present three cases of severe hypotensive shock due to chlorpromazine. All three cases had previously been treated uneventfully with this medication. We therefore believe that hypersensitivity might be the cause. All patients who have a history of having taken chlorpromazine previously should be given a sensitivity test before the drug is administered again.
Submitted on May 3, 1972
