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The British Journal of Psychiatry (1969) 115: 1185-1188. doi: 10.1192/bjp.115.527.1185
© 1969 The Royal College of Psychiatrists
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The Effect of Lithium Carbonate on the Electroencephalogram of Patients with Affective Disorders

S. R. PLATMAN M.D.1 and R. R. FIEVE M.D.2

1 Research Associate, Department of Psychiatry, Columbia University, and Associate Research Scientist, New York State Psychiatric Institute
2 Assistant Professor, Department of Psychiatry, Columbia University; Research Chief, New York State Psychiatric Institute

A double-blind study was performed on forty-five manic-depressive patients. There was no difference in the number of abnormal EEG patterns in the manic, depressed and normal states.

Fifteen of twenty-eight patients showed increasingly abnormal EEGs when placed on lithium carbonate. This is not related to sex, age, serum lithium level, clinical state or therapeutic outcome.

Submitted on September 6, 1968







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Copyright © 1969 The Royal College of Psychiatrists.